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KMID : 1123920100240020319
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Korean Journal of Oriental Physiology and Pathology
2010 Volume.24 No. 2 p.319 ~ p.327
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Effects of Mageum-tang on the Hyperlipidemia in Rats
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Roh Seung-Won
Kim Jeung-Beum
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Abstract
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This study was designed to investigate the hyperlipidemia-healing effect of liquid extract from Mageum-tang(麻芩湯), it was performed on the hyperlipidemia of rats induced by high cholesterol diet and Triton WR-1339. We prepared two types of hyperlipidemia model in rats induced by high cholesterol diet and Triton WR-1339. The amount of total cholesterol, HDL-cholesterol, LDL -cholesterol, triglyceride, phospholipid, free fatty acid, the activity of superoxide dismutase(SOD), and glutathione were measured. The liquid extract from Mageum-tang showed significant decreasing effects on total cholesterol, LDL- cholesterol, triglyceride, phospholipid, free fatty acid in the both model. And it showed significant increasing effects on HDL-cholesterol, the activity of SOD in both model and amount of glutathione in Triton WR-1339 model. These results suggest that liquid extract from Mageum-tang has healing efficacy on hyperlipidemia induced by high cholesterol diet and Triton WR-1339.
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KEYWORD
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Mageum-tang(麻芩湯), hyperlipidemia, total cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol
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